Preheat the oven to 400 degrees F (200 degrees C). Grease a 10x13-inch baking dish with cooking spray.

Mix together cottage cheese, beaten eggs, Monterey Jack cheese, green chiles, melted butter, flour, bacon, and baking powder in a large bowl until well combined; pour into the prepared baking dish.

Bake in the preheated oven for 15 minutes. Reduce heat to 350 degrees F (175 degrees C) and continue baking until a toothpick inserted into the center of casserole comes out clean, about 30 minutes more.