Gather all ingredients and preheat the smoker to 250 degrees F (120 degrees C). Add wood chips according to the manufacturer’s directions.

Combine salt, brown sugar, pepper, paprika, ground mustard, garlic powder, onion powder, and oregano in a small bowl. Sprinkle over both sides of pork chops.

Place pork chops, unstacked, onto the smoker grate and cook in the preheated smoker for 2 hours 30 minutes. Remove chops from the smoker and let rest for 10 minutes.