Gather all ingredients.

Preheat the oven to 425 degrees F (220 degrees C).

Mix mayonnaise, Parmesan cheese, and garlic powder together in a bowl.

Place bread crumbs in a separate bowl. Dip each chicken breast into the mayonnaise mixture, then into the bread crumbs to coat

Arrange breaded chicken on a baking sheet.

Bake in the preheated oven until chicken is no longer pink in the center and the coating is golden brown, about 20 minutes. An instant-read thermometer inserted into the center should read at least 165 degrees F (74 degrees C).

Serve hot and enjoy!